The film chronicles Dr. Thompson’s successful attempt to avoid being placed in the system – jail and/or rehabilitation – by rogue Aspen City cops that conspired to bust him for drunken driving on the eve of an important local election. This political story interweaves with his struggle to bring his book “Fear and Loathing in Las Vegas” to a proper life as a feature film starring Johnny Depp and Benicio Del Toro. The cast of characters he meets on his odyssey, in addition to Depp and Del Toro also include songwriter Warren Zevon, actor John Cusack, artist Ralph Steadman, and fellow journalists George Plimpton and P.J. O’Rourke.